I had one wire for the skull and vertebrae. Another running through both legs (connected at the pelvis). Two for each arm and some peripheral wires for the finger and toes.
I used 16 gauge stainless steel wire. It was fine for the arms and legs but too heavy to hold its own weight across the tail. If I were to make this project again I'd probably try using two lines of thinner wire along the vertebrae, displaced vertically, so that it had better bending resistance.
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